Clinical Trials Directory

Trials / Unknown

UnknownNCT03374280

Pemetrexed/Cisplatin Intercalating Gefitinib Treating EGFR Wild NSCLC

The Phase Three Trials of Pemetrexed/Cisplatin Intercalating Gefitinib vs Pemetrexed/Cisplatin Treating EGFR Wild NSCLC(Non Squamous Cell Carcinoma)

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
178 (estimated)
Sponsor
Guangzhou Medical University · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

To investigate the curative effect between Pemetrexed/Cisplatin and Pemetrexed/Cisplatin intercalating Gefitinib Treating EGFR Wild NSCLC

Detailed description

In preclinical data, it is identified that pemetrexed combined with erlotinib could achieve good response than pemetrexed because EGFR-TKI (erlotinib) could enhance the sensitivity of pemetrexed. So we design the trial to investigate curative effect between Pemetrexed/Cisplatin and Pemetrexed/Cisplatin intercalating Gefitinib Treating EGFR Wild NSCLC.

Conditions

Interventions

TypeNameDescription
DRUGpemetrexed/cisplatin intercalating gefitinib
DRUGpemetrexed/cisplatin

Timeline

Start date
2016-12-01
Primary completion
2019-12-30
Completion
2021-12-30
First posted
2017-12-15
Last updated
2019-03-28

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03374280. Inclusion in this directory is not an endorsement.