NCT03374163

Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 142 (actual)
• Sponsor: King Fahad Medical City · Other Government
• Sex: Female
• Age: 21 Years – 42 Years
• Healthy volunteers: Accepted

Summary

To evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI).

Detailed description

the aim to evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI). A total of 142 patients with history of unexplained RIF3 or more cycles were included in the study. Patient were randomized into two groups, study group (n=71) and control group (n=71). The study groupreceivedintralipid 20%infusionon the day of embryo transfer (ET) and a second dose on the day of pregnancy test. The control group underwent ET without intralipidinfusion.Allpatientswereclosely monitored for any side effectsincluding allergic reactions.

Conditions

• Infertility Due to Nonimplantation

Interventions

Type	Name	Description
DRUG	intralipid 20%	milky soulation for energey supplement.

Timeline

• Start date: 2015-01-01
• Primary completion: 2017-06-30
• Completion: 2017-06-30
• First posted: 2017-12-15
• Last updated: 2017-12-15

Regulatory

• FDA-regulated drug study