NCT03373656

Vaccination for Children of H&O and Their Parents

Study on Compliance, Safety and Effectivity of Vaccination for Children With Hematologic Malignancies or Solid Tumors and Their Parents

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Children's Cancer Group, China · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to study on compliance, safety and effectivity of vaccination for children with hematologic malignancies or solid tumors and their parents.

Detailed description

Children with hematologic malignancies or solid tumors are all facing with immune deficiency due to the disease, the chemotherapy, the hematopoietic stem cell transplantation or the splenectomy, which greatly increases their chance to get infectious diseases. In this study, we will assess the compliance of children with hematologic malignancies or solid tumors and their parents to accept vaccination after finishing treatments, follow up with untoward effect questionnaires to assess the safety, obtain the serum of children patients to test antibody titers and assess the effectivity, provide clues for the study of vaccination in children with hematologic malignancies or solid tumors and provide a scientific basis for the formulation and reunification of vaccination programs.

Conditions

• Vaccination
• Hematologic Malignancy
• Solid Tumor, Childhood

Interventions

Type	Name	Description
BIOLOGICAL	Vaccination	Patients with higher antibody titers will accept vaccination. There are two vaccines provided in this study: hepatitis B vaccine measles-rubella combined vaccine
OTHER	No Vaccination	Patients with higher antibody titers will NOT accept vaccination. But we will keep monitoring their antibody titers.

Timeline

• Start date: 2017-05-01
• Primary completion: 2025-07-01
• Completion: 2025-09-01
• First posted: 2017-12-14
• Last updated: 2022-07-26

Locations

1 site across 1 country: China