NCT03373357

Hypertension and Cardiovascular Risk Associated With Obstructive Sleep Apnea in Adult in Guadeloupe (French West Indies)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 220 (actual)
• Sponsor: Centre Hospitalier Universitaire de la Guadeloupe · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The MAPA is the reference method to estimate the PA during the SAHOS. The MAPA can be recommended over 48 hours: indeed, the PA falls at the beginning of every apnea then increases gradually up to a pressif peak arising at the time of the ventilatoire resumption. These variations arise under the influence of 4 stimulus: the désaturation in O2, the rise of the PaCO2, the increase of the respiratory effort and the microawakening of the end of apnea who are at the origin of a sympathetic stimulation. Consequently a better diagnostic approach of the HTA (confirmation of a resistant HTA, an identification of the masked HTA and the patients " not dipper " by the MAPA), the identification of the SAHOS, and a better coverage) of the associated cardiovascular risk factors are essential and establish a stake in public health. To investigator's knowledge, no datum or study on the association HTA-SAHOS and its consequences was until then realized in the French overseas departments.

Detailed description

In Guadeloupe, data on the relationships between arterial hypertension and obstructive sleep apnea are unavailable. The aim of this study was: to assess the frequency of hypertension and non-dipper pattern evaluated by 48-hour ambulatory blood pressure monitoring in an adult population identified obstructive sleep apnea/non-obstructive sleep apnea during overnight polygraphy ; to determine the cardio-metabolic factors associated with obstructive sleep apnea.

Conditions

• Hypertension Arterial

Interventions

Type	Name	Description
OTHER	Patient not SAHOS	Phone consultation in 1 month, 3mois, then every 6 months, and an annual visit. * Cardiovascular events arisen during the duration of the study * Modifications of the lifestyle: alcohol, physical activity * Weight * Clinical measure of the PA * Clinical examination * The collection of the cardiovascular events arisen during the duration of the study will be realized for all the inclusive patients
OTHER	Patient SAHOS sailed by the ventilation in PPC and not sailed	Questionnaire of subjective evaluation of diurnal slumber: scale of Epworth and search for appearance of at least 2 of the following symptoms: sleep not salvage dealer, night-breathlessnesses, multiple awakenings, fatigue, disordersconfusions, nycturie, snore. * Questionnaire of evaluation of the global quality of life of the SAHOS * Appearance of new cardiovascular risk factors * Cardiovascular events arisen during the duration of the study * Modification of the current treatments * Modifications of the lifestyle: alcohol, physical activity * Weight * Clinical measure of the PA * Clinical examination * The collection of the cardiovascular events arisen during the duration of the study will be realized for all the inclusive patients

Timeline

• Start date: 2008-09-09
• Primary completion: 2014-11-19
• Completion: 2019-11-30
• First posted: 2017-12-14
• Last updated: 2017-12-14

Locations

1 site across 1 country: Guadeloupe