NCT03372616

coMparison Between invAsive and Non-invasive assessmenT on Blood Pressure and Cardiac Function in HealthY Participants

coMparison Between invAsive and Non-invasive assessmenT on Blood Pressure and Cardiac Function in HealthY Participants: the MATCHY Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This is a cross-sectional cohort study which aims to compare the invasive and non-invasive assessments on aortic blood pressure and cardiac funtion in subjects without history of cardio-vascular disease. Left ventricular (LV) filling pressure, LV volume, and aortic blood pressure will be measured invasively. Non-invasive assessment includes echocardiography,aortic, and carotid blood pressure measurement.

Conditions

• Healthy Volunteer

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Invasive left ventricular diastolic function assessment	Left ventricular (LV) polyethylene catheter was inserted into left ventricular to directly measure LV filling pressure.
DIAGNOSTIC_TEST	Invasive aortic blood pressure measurement	Aortic blood pressure will be measured with polyethylene catheter in aortic root.
DIAGNOSTIC_TEST	Non-Invasive left ventricular diastolic function assessment	Echocardiography will be performed in all participants to assess left ventricular diastolic function non-invasively.
DIAGNOSTIC_TEST	Non-Invasive aortic blood pressure measurement	Three devices (Sphygmocor \[AtCor Medical, Australia\], PulsePen \[DiaTecne SRL, Italy\], and Mobil-O-Graph \[IEM, Germany\] ) will be used to assess aortic blood pressure non-invasively when participants are undergoing invasive aortic blood pressure measurement.

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-03-01
• Completion: 2018-06-01
• First posted: 2017-12-13
• Last updated: 2017-12-13