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CompletedNCT03372096

LC Bead LUMI for Prostatic Artery Embolization

LC Bead LUMI for Prostatic Artery Embolization: A Pilot Study

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
18 (actual)
Sponsor
University of North Carolina, Chapel Hill · Academic / Other
Sex
Male
Age
40 Years
Healthy volunteers
Not accepted

Summary

Purpose: The purpose of this pilot study is to determine preliminary estimates of the parameters related to the distribution of the study endpoints including: International Prostate Symptom Score (IPSS) and quality of life (QoL) score changes, Qmax (maximum urine flow rate) changes, post void residual volume (PVR) changes, percent prostate infarction and presence of non-target embolization. Participants: 20 adult male subjects with benign hyperplasia will be enrolled in this study. Procedures (methods): This will be a multisite, open label pilot study with a small population undergoing an investigational intervention (prostatic artery embolization) to determine initial safety and potential for efficacy as measured by improvement of lower urinary tract symptoms (LUTS) and decrease in prostate size.

Detailed description

This will be an open label pilot study with a small population undergoing an intervention to determine initial safety and potential for efficacy as measured by improvement of LUTS and decrease in prostate size

Conditions

Interventions

TypeNameDescription
DEVICEProstatic Artery EmbolizationLC Bead LUMI is a spherical polyvinyl alcohol embolic particle that incorporates radiopaque moieties. Once a catheter has been fluoroscopically guided into the target vessel, the beads are then injected, causing obstruction at the arteriole level until the desired degree of embolization has occurred.

Timeline

Start date
2018-07-13
Primary completion
2020-09-03
Completion
2020-09-03
First posted
2017-12-13
Last updated
2021-02-24
Results posted
2021-02-05

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03372096. Inclusion in this directory is not an endorsement.

LC Bead LUMI for Prostatic Artery Embolization (NCT03372096) · Clinical Trials Directory