NCT03371537

Study of Hemodynamic Conditions Measured During Hepatectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 9 (actual)
• Sponsor: University Hospital, Tours · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hepatocellular insufficiency is a dreaded complication after hepatectomy, since, if it is persistent, it leads to the death of the patient in the absence of liver transplantation. The preoperative evaluation aims in particular to estimate the risk of postoperative hepatocellular insufficiency so as to minimize or contraindicate high-risk patients. It has been shown that the flow of the portal vein is correlated with liver function, especially in the living donor and after portal embolization. More recently, the study of flow rates in the portal vein and the hepatic artery after transplantation has shown a correlation with the recovery of graft function. The hypothesis is that portal and arterial flow after hepatectomy can predict postoperative hepatocellular function.

Detailed description

Measurements of flow rates in the portal vein and the hepatic artery by different transit times are available thanks to the Medistim VeriQTM system that the investigators already use routinely in the context of liver transplantation when performing hepatectomies.

Conditions

• Liver Dysfunction
• Circulatory; Change

Interventions

Type	Name	Description
PROCEDURE	Liver debit measure	Mesure of liver debit during hepatectomy

Timeline

• Start date: 2017-10-08
• Primary completion: 2019-03-19
• Completion: 2019-03-19
• First posted: 2017-12-13
• Last updated: 2021-03-18

Locations

1 site across 1 country: France