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Trials / Completed

CompletedNCT03371264

Data Collection Study From Donors and Recipients to Optimize Donor-recipient Matching in Liver Transplantation

Optimizing Donor-recipient Matching to Improve Survival After Registration on the Waiting List for Liver Transplantation: the OPTIMATCH LT Study

Status
Completed
Phase
Study type
Observational
Enrollment
9,000 (actual)
Sponsor
Assistance Publique - Hôpitaux de Paris · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers

Summary

A major limitation of liver transplantation is organ shortage. To avoid exposing patients to death on the waiting list, organs are used that would have been discarded few years ago. Graft allocation is regulated by the "agence de biomedecine" which establishes a national score. Each liver graft is proposed to the patient presenting the higher score. Acceptance or rejection of the graft only depends on the decision of each centre. We propose to submit a more efficient allocation model (enabling each proposed liver graft to be transplanted in the candidate whose transplantation will afford the greatest survival benefit after registration), by collecting and analysing variables from donors and candidates/recipients.

Conditions

Timeline

Start date
2015-01-01
Primary completion
2018-01-01
Completion
2020-01-01
First posted
2017-12-13
Last updated
2020-12-14

Source: ClinicalTrials.gov record NCT03371264. Inclusion in this directory is not an endorsement.

Data Collection Study From Donors and Recipients to Optimize Donor-recipient Matching in Liver Transplantation (NCT03371264) · Clinical Trials Directory