NCT03370692

Prognostic Score in the Very Old ICU Patients

Development and Validation of a Prognostic Score in the Very Old ICU Patients (≥80 Years)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,900 (actual)
• Sponsor: University of Bergen · Academic / Other
• Sex: All
• Age: 80 Years
• Healthy volunteers: Not accepted

Summary

The two main aims of the study: 1. To investigate the relation of Frailty, Activity of daily life (ADL), Cognitive functions and Co-morbidity on survival at 30 days (and 6 months in a substudy) 2. From the results design a prognostic score that will be validated using a subpopulation of the study cohort Two secondary aims a 1. Survival at 6 months (in a subpopulation of the study) 2. An inter-rater validation of the Clinical Frailty Score (CFS) (in a subpopulation) Substudies are planned with regards to the different admission categories, in particular: * trauma * acute respiratory failure * sepsis * combined respiratory and circulatory failure * medical neurological conditions In some of the substudies similar groups from the VIP1 study that uses the same admission categories (except planned admissions) will be merged.

Detailed description

Frailty to be registered by the Clinical Frailty Scale (CFS), 1-9 point Activity of Daily life (ADL) with Katz ADL form: 0-6 points Cognition to be described by Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) questionaire, 16 questions to be asked the care-givers Co-morbidity by listing the major comorbidity with Yes or No (Yes= 1 point) and with the number of regular drugs prescribed

Conditions

• Aged, 80 and Over
• Critical Care

Interventions

Type	Name	Description
OTHER	Cognitive assesment, Frailty assessment	Asking relatives (using a structured questionaire) about cognitive function at admission , likewise about frailty using the Clinical Frailty Score

Timeline

• Start date: 2018-05-01
• Primary completion: 2019-11-01
• Completion: 2019-11-01
• First posted: 2017-12-12
• Last updated: 2021-04-28

Locations

1 site across 1 country: Norway