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Trials / Completed

CompletedNCT03366428

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer

Phase 1, Multicenter, Open-label, Multiple-dose Study of DS-8201a to Assess the Effect on the QT Interval and Pharmacokinetics in Subjects With HER2-expressing Metastatic and/or Unresectable Breast Cancer

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
51 (actual)
Sponsor
Daiichi Sankyo Co., Ltd. · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

This study will look at the effect on the QTc interval and pharmacokinetics after multiple dosing in subjects with HER2-expressing metastatic and/or unresectable breast cancer.

Conditions

Interventions

TypeNameDescription
DRUGDS-8201aDS-8201a is supplied as a lyophilized powder which is reconstituted for infusion

Timeline

Start date
2017-12-26
Primary completion
2018-12-05
Completion
2021-02-19
First posted
2017-12-08
Last updated
2022-04-12
Results posted
2021-06-14

Locations

7 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT03366428. Inclusion in this directory is not an endorsement.

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast C (NCT03366428) · Clinical Trials Directory