Trials / Completed
CompletedNCT03364556
Nutritional Intake and Bone Health in Celiac Disease
Nutritional Intake and Bone Health Among Adults With Undiagnosed, Untreated Celiac Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 13,893 (actual)
- Sponsor
- George Mason University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Celiac disease leads to malnutrition and secondary conditions including osteoporosis. The dietary habits of adults with untreated, undiagnosed celiac disease has not yet been observed, but presents a critical piece in understanding the effects of the disease on bone health. Objective was to evaluate differences in nutritional intake of calcium, vitamin D, and phosphorus; serologic indices of these nutrients; and bone health among adults with and without celiac disease. Cross-sectional data from What We Eat in America (WWEIA) and the National Health and Nutrition Examination Survey (NHANES) 2009-14 was analyzed.
Detailed description
Celiac disease leads to malnutrition and secondary conditions including osteoporosis. The dietary habits of adults with untreated, undiagnosed celiac disease has not yet been observed, but presents a critical piece in understanding the effects of the disease on bone health. Objective was to evaluate differences in nutritional intake of calcium, vitamin D, and phosphorus; serologic indices of these nutrients; and bone health among adults with and without celiac disease. Cross-sectional data from What We Eat in America (WWEIA) and the National Health and Nutrition Examination Survey (NHANES) 2009-14 was analyzed, including self-reported dietary and supplement intake from one day of 24-hour recalls, serologic indicators, and dual x-ray absorptiometry (DXA) scans were analyzed in adults (n=49) testing positive for celiac disease to the tissue transglutaminase endomysial antibody assay (tTG-EMA). Statistical analysis included multiple linear regression modelling controlled for age, sex, race/ethnicity, energy intake, and poverty income ratio.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No intervention |
Timeline
- Start date
- 2016-06-01
- Primary completion
- 2017-11-01
- Completion
- 2017-11-01
- First posted
- 2017-12-06
- Last updated
- 2017-12-06
Source: ClinicalTrials.gov record NCT03364556. Inclusion in this directory is not an endorsement.