NCT03362203

Conditioned Pain Modulation in Chronic Neck Pain Patients

The Hypersensitivity and Changes of Conditioned Pain Modulation in Chronic Neck Pain Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 21 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The aim of this study was to evaluate changes in local and segmental hypersensitivity and endogenous pain inhibition in people with chronic nonspecific neck pain.

Detailed description

Quantitative sensory testing is widely used in human research to investigate the state of the peripheral and central nervous system contributions in pain processing. It is a valuable tool to help identify central sensitization and may be important in the treatment of chronic neck pain. This study is a cross-sectional study. Two groups including chronic neck pain group and healthy volunteers group will be arranged in this study. The healthy subjects will be matched for sex and age in relation to the neck pain group. The pressure pain threshold (PPT) will be measured at the neck muscle in both groups. The cold pressor test will be used in both groups to activate conditioned pain modulation.

Conditions

• Neck Pain

Interventions

Type	Name	Description
OTHER	Patients with chronic neck pain	Patients,aged 21-80 years, must have experienced neck pain for at least 3 months and have reported a minimal pain level of 30 (pain threshold) on the 0-100 pain numerical rating scale (NRS) in the last 7 days.
OTHER	Subjects without chronic neck pain	Subjects,aged 21-80 years, must not have presented episodes of chronic neck pain for more than 7 days in the last 12 months.

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-08-01
• Completion: 2018-08-01
• First posted: 2017-12-05
• Last updated: 2017-12-05

Locations

1 site across 1 country: China