NCT03361618

Effect of Oral Zinc Sulfate Supplementation on Enzymes of Urate Pathway

Effect of Oral Zinc Sulfate Supplementation on Enzymes of Urate Pathway in Spermatozoa and Seminal Plasma of Iraqi Asthenospermic Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Babylon University · Academic / Other
• Sex: Male
• Age: 26 Years – 36 Years
• Healthy volunteers: Accepted

Summary

Although many reports have investigated the relationship between subfertility and uric acid levels in semen, to the best of author knowledge, there is no study have been published to yet focus on the effects of asthenospermia treatments, such as given an oral zinc supplementation, on the activity of urate-related enzymes, which are important in fertility of human.

Detailed description

The present study was designed to investigate the effect of zinc supplementation on the qualitative and quantitative characteristics of semen, along with uric acid levels and urate-related enzymes in the seminal plasma and spermatozoa of asthenospermic males.

Conditions

• Infertility Unexplained

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Zinc Sulfate	The subfertile group treated with zinc sulfate, every participant took two capsules of zinc sulfate per day for three months (each one 220 mg).

Timeline

• Start date: 2011-07-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2017-12-05
• Last updated: 2017-12-05

Locations

1 site across 1 country: Iraq