NCT03360123

Comparison of Triazolam and Midazolam for Anxiolysis During Dental Treatment in the Pediatric Patient

Oral Anxiolysis for the Older Pediatric Patient-Which Medication is Preferred?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: All
• Age: 7 Years – 17 Years
• Healthy volunteers: Accepted

Summary

This study will evaluate the perceptions of the effects of two anxiolytic medications commonly used during dental treatment in patients weighing 40 kilograms or more.

Detailed description

Midazolam and nitrous oxide are commonly used in pediatric patients requiring anxiolysis during dental treatment. Triazolam and nitrous oxide are commonly used in adult patients requiring anxiolysis during dental treatment. The participants in this study are patients already scheduled for 2 sedation appointments to complete their dental treatment. The medications are both benzodiazepines that have similar risks, neither medication has greater adverse effects than the other. This study will evaluate the perceptions of the effects of the medications via a parent survey and chart review. The goal of the study is to determine which anxiolytic medication is perceived to provide a better sedation experience for older pediatric patients based on parent perception of the medication's effects and the patient's behavior during dental treatment.

Conditions

• Dental Anxiety

Interventions

Type	Name	Description
DRUG	Midazolam Hydrochloride 2Mg/mL Syrup	Midazolam HCl Syrup 0.5mg/kg (Max: 15mg) taken 10-15 minutes prior to dental treatment.
DRUG	Triazolam 0.125 MG	Triazolam: 0.125mg tablet taken 30 minutes prior to dental treatment.

Timeline

• Start date: 2018-01-26
• Primary completion: 2018-04-11
• Completion: 2018-04-11
• First posted: 2017-12-02
• Last updated: 2018-06-19

Locations

1 site across 1 country: United States