NCT03360045

Comparing Effectiveness of Merocel and Packing With Tranexamic Acid in the Management of Anterior Epistaxis

The Evaluation of Effectiveness of Nasal Compression With Tranexamic Acid Compared to Simple Nasal Compression and Merocel Packing

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 135 (actual)
• Sponsor: Kecioren Education and Training Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Aim of this study is evaluate whether superior nasal compression with tranexamic acid to simple nasal compression and Merocel packing. In this study, patients who presented with non-traumatic anterior epistaxis to emergency departments will be included in this study. Three different therapy option are created; first, nasal compression with tranexamic acid, second, simple nasal compression without any drugs. And third, packing with Merocel.

Conditions

• Tranexamic Acid
• Epistaxis
• Nasal Packing

Interventions

Type	Name	Description
DRUG	Tranexamic Acid	500mg tranexamic acid is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
DRUG	Normal saline	5 cc normal saline is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
DEVICE	Merocel	Merocel packing is applied.

Timeline

• Start date: 2018-05-01
• Primary completion: 2018-08-01
• Completion: 2018-08-01
• First posted: 2017-12-02
• Last updated: 2018-08-07

Locations

1 site across 1 country: Turkey (Türkiye)