NCT03352700

Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 580 (estimated)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 3L PEG before colonoscopy. Patients in group B (n = 300) were additionally advised to Dyclonine Hydrochloride Mucilage plus 3L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by a single endoscopist who was blinded to the intervention. Visibility was blindly assessed for the amount of air bubbles and adenoma detection rate (ADR). Difficulty of procedure, and adverse events were also evaluated.

Conditions

• Bowel Preparation Scale
• the Amount of Air Bubble
• Adenoma Detection Rate

Interventions

Type	Name	Description
DRUG	3L PEG	Group A patients (n = 300) used only 3L PEG before colonoscopy.
DRUG	3L PEG+Dyclonine Hydrochloride Mucilage	Patients in group B (n = 300) were additionally advised to Dyclonine Hydrochloride Mucilage plus 3 L PEG

Timeline

• Start date: 2017-12-01
• Primary completion: 2018-01-01
• Completion: 2018-02-01
• First posted: 2017-11-24
• Last updated: 2017-11-24

Locations

1 site across 1 country: China