Clinical Trials Directory

Trials / Completed

CompletedNCT03351816

Impact of New Biomarkers on Maintenance of Sinus Rhythm After Cardioversion or Ablation of Atrial Fibrillation

Impact of New Biomarkers on the Maintenance of Sinus Rhythm After Cardioversion or Ablation of Atrial Fibrillation

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
106 (actual)
Sponsor
Centre Hospitalier Universitaire de Besancon · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The Biorhythm study aims to investigate the utility of new biomarkers (e.g. MR proANP, ST2) measured pre-procedure for the prediction of procedural success in patients with atrial fibrillation undergoing cardioversion or ablation.

Detailed description

This is a prospective, observational, multicentre study of patients with paroxystic or persistent atrial fibrillation scheduled to undergo cardioversion or ablation of AF in routine practice. Serum levels of MR proANP and ST2 pre-procedure will be measured to attempt to identify a threshold that carries prognostic value for procedural success (maintenance of sinus rhythm at one year).

Conditions

Interventions

TypeNameDescription
PROCEDUREAblation of atrial fibrillationPulmonary vein isolation by radiofrequency or cryoablation.
PROCEDURECardioversionExternal electric shock delivery under general anesthesia.

Timeline

Start date
2017-12-01
Primary completion
2019-03-31
Completion
2020-06-01
First posted
2017-11-24
Last updated
2020-12-23

Locations

3 sites across 1 country: France

Source: ClinicalTrials.gov record NCT03351816. Inclusion in this directory is not an endorsement.