NCT03351543

Effect of Microbial Exposure on Health, Particularly Immune System

ADELE: Autoimmune Defense and Living Environment

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of Helsinki · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The effect of microbial exposure on healthy human subjects will be investigated. Changes in cytokine and IgE and vaccine response will be measured. The hypothesis is that microbial exposure increases the measured responses.

Detailed description

The effect of microbial exposure on healthy human subjects will be investigated. The volunteers will either receive material containing a microbial inoculum, or they will receive nothing. Changes in cytokine and IgE and vaccine response will be measured. Subjective well-being will be recorded. Changes in microbial community will be followed. The hypothesis is that microbial exposure increases the measured responses.

Conditions

• Immune System Disorders

Interventions

Type	Name	Description
BIOLOGICAL	microbial inoculate	volunteers will regularly receive microbial inoculate that they do not use orally

Timeline

• Start date: 2016-03-01
• Primary completion: 2016-06-01
• Completion: 2017-07-01
• First posted: 2017-11-24
• Last updated: 2017-11-24

Locations

1 site across 1 country: Finland