Clinical Trials Directory

Trials / Completed

CompletedNCT03350347

A Study of Molidustat for Maintenance Treatment of Renal Anemia in Non-dialysis Subjects

A Randomized, Open-label, Active-controlled, Parallel-group, Multicenter Study to Investigate the Efficacy and Safety of Oral Molidustat in Comparison to Darbepoetin Alfa in Non-dialysis Subjects Previously Treated With Erythropoiesis-Stimulating Agents (ESAs)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
164 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of molidustat in non-dialysis subjects previously treated with Erythropoiesis-Stimulating Agents (ESAs)

Conditions

Interventions

TypeNameDescription
DRUGMolidustat (BAY85-3934)Starting dose of 25 mg or 50 mg molidustat once daily (OD) will be titrated based on the subject's Hb response
DRUGDarbepoetin alfaStarting dose and frequency of darbepoetin alfa are based on previous ESA. The dose will be titrated based on the subject's Hb response

Timeline

Start date
2017-12-13
Primary completion
2019-07-05
Completion
2019-11-28
First posted
2017-11-22
Last updated
2021-01-29

Locations

59 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT03350347. Inclusion in this directory is not an endorsement.

A Study of Molidustat for Maintenance Treatment of Renal Anemia in Non-dialysis Subjects (NCT03350347) · Clinical Trials Directory