NCT03350334

Perioperative Duloxetine for Pain Management After Laparoscopic Hysterectomy

Perioperative Duloxetine for Pain Management After Laparoscopic Hysterectomy: A Prospective Randomized Placebo-controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Acibadem University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the investigators of the study is to evaluate the effect of peri-operative duloxetine on post-operative recovery in patients undergoing laparoscopic hysterectomy.

Detailed description

Patients with benign gynecologic conditions (fibroids, pelvic pain, uterine prolapse) who are planned to undergo laparoscopic hysterectomy will be enrolled in the study. After randomization, the study participants will be given 60 mg duloxetine 2 hours before surgery and 24 hours after surgery, whereas the control participants will be given placebo tablets.

Conditions

• Laparoscopic Hysterectomy
• Postoperative Recovery
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Duloxetine	Peri-operative Duloxetine administration
DRUG	placebo	Placebo administration

Timeline

• Start date: 2017-12-04
• Primary completion: 2018-03-10
• Completion: 2018-03-15
• First posted: 2017-11-22
• Last updated: 2018-05-16

Locations

1 site across 1 country: Turkey (Türkiye)