NCT03347032

Remote Ischemic Preconditioning for Renal Protection in TAVI

Remote Ischemic Preconditioning for Renal Protection in Patients Undergoing Transcatheter Aortic Valve Interventions

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Henry Ford Health System · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Severe aortic stenosis remains a major cause of morbidity and mortality of the elderly affecting approximately 3% of elderly patients with an increasing number of patients undergoing transcatheter aortic valve interventions. As part of pre-procedural planning these patients undergo CT scans and receive contrast during the procedure. These patients often have baseline renal insufficiency and are high risk of contrast induced nephropathy despite pre-hydration techniques. The purpose of this study is to evaluate the efficacy of this simple and safe procedure in preventing renal injury in this particular population.

Conditions

• Aortic Valve Stenosis
• Renal Insufficiency
• Contrast-induced Nephropathy

Interventions

Type	Name	Description
PROCEDURE	Remote ischemic preconditioning	Serial inflations and deflations as detailed in the arm/group descriptions
PROCEDURE	Control	Serial inflations and deflations as detailed in the arm/group descriptions

Timeline

• Start date: 2018-02-13
• Primary completion: 2018-12-30
• Completion: 2018-12-30
• First posted: 2017-11-20
• Last updated: 2022-12-14

Locations

1 site across 1 country: United States