NCT03346330

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food-effect of TRK-750

An Exploratory, Randomised, Double-blind, Placebo-controlled, Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food-effect of TRK-750 in Healthy Adults and Patients With Peripheral Neuropathic Pain

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: Toray Industries, Inc · Industry
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This is an exploratory, randomised, double-blind, placebo-controlled, Phase I study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food-effect of single and multiple, ascending oral doses of TRK-750 in healthy adults and patients with peripheral neuropathic pain.

Conditions

• Healthy, Peripheral Neuropathic Pain

Interventions

Type	Name	Description
DRUG	TRK-750	TRK-750 capsule
DRUG	Placebo	Placebo capsule

Timeline

• Start date: 2017-11-21
• Primary completion: 2018-08-31
• Completion: 2018-08-31
• First posted: 2017-11-17
• Last updated: 2018-12-19

Locations

1 site across 1 country: United Kingdom