NCT03344432

Correlation Intraocular Pressure With Intracranial Pressure

Correlation of Intraocular Pressure With Intracranial Pressure in Childs With Severe Trauma Brain Injury

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Hospital Civil de Guadalajara · Academic / Other
• Sex: All
• Age: 2 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.

Detailed description

Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values. Material and methods. Correlation and diagnostic test design study. Inclusion criteria: children with TBIs admitted to the emergency room and indication of catheter for ICP measurement. Exclusion criteria: injury or ophthalmic disease, glaucoma, encephalic death. Intraocular pressure was measured with electronic tonometer in both eyes prior to placement of the catheter for ICP measurement. Correlation was estimated with Spearman's Rho. The utility values of the diagnostic test were obtained from an Receiver Operating Characteristic curve.

Conditions

• Intraocular Pressure
• Intracranial Pressure Increase
• Trauma, Brain
• Children, Only

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	with intraocular pressure high	Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.
DIAGNOSTIC_TEST	without intraocular pressure high	Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

Timeline

• Start date: 2015-06-10
• Primary completion: 2017-11-30
• Completion: 2019-12-31
• First posted: 2017-11-17
• Last updated: 2017-11-17

Locations

1 site across 1 country: Mexico

Regulatory

• FDA-regulated device study