NCT03343938

Evaluation of a Closed Assisted Reproductive Technology (ART) Station Versus an Open Flow Cabinet

Comparative Study Between Two Systems of Gamete and Embryo Handling: Closed Environment Versus Open System

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Vida Recoletas Sevilla · Academic / Other
• Sex: All
• Age: 18 Years – 49 Years
• Healthy volunteers: Not accepted

Summary

There is not yet a standardized system of human embryonic culture in vitro. In addition, technical improvements continually appear. The investigators recently carried out a study in which it shows that the grouped embryo culture at low oxygen tension (5% O2) in a benchtop incubator shows better success rates than individual culture at atmospheric oxygen tension (20% O2) in a conventional incubator. For these reasons, the investigators have decided to continue this research line to evaluate the efficacy of a new ART station with a closed environment in comparison of an open flow cabinet. This new system keeps a controled environment maintaining a carbon dioxide (CO2) concentration of 6% and a temperature of 37 degrees. A prospective randomized study will be carried out in which the manipulation of the gametes and pre-embryos of the patients will be carried out in open laminar flow cabinets or in a closed station that maintain the CO2 and temperature conditions.

Conditions

• ART

Interventions

Type	Name	Description
OTHER	Embryo handling in a closed station	Embryo handling is performed inside a closed station with a controlled environment: 6% CO2 and 37 degrees.

Timeline

• Start date: 2017-10-31
• Primary completion: 2019-10-31
• Completion: 2019-11-30
• First posted: 2017-11-17
• Last updated: 2020-02-12

Locations

1 site across 1 country: Spain