Clinical Trials Directory

Trials / Terminated

TerminatedNCT03342859

Mode of Action Study of Vilaprisan and Ulipristal Acetate in Patients With Uterine Fibroids for Whom Surgery is Planned

An Open-label, Parallel Group, Multi-center Study to Investigate Pharmacodynamic Effects After Daily Administration of Vilaprisan or Ulipristal Acetate for 8-12 Weeks in Patients With Uterine Fibroids for Whom Surgery (Hysterectomy or Myomectomy) is Planned

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
10 (actual)
Sponsor
Bayer · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

To investigate the clinical effects of vilaprisan and ulipristal acetate at molecular and cellular level on uterine and fibroid tissue taken from patients (after surgery / biopsy)

Conditions

Interventions

TypeNameDescription
DRUGVilaprisan, BAY1002670Daily single oral doses of 2 mg vilaprisan over 8-12 weeks
DRUGUlipristalDaily single oral doses of 5 mg ulipristal over 8-12 weeks

Timeline

Start date
2017-11-16
Primary completion
2018-12-17
Completion
2020-01-13
First posted
2017-11-17
Last updated
2021-01-06

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT03342859. Inclusion in this directory is not an endorsement.