Clinical Trials Directory

Trials / Terminated

TerminatedNCT03342365

Evaluation of Intestinal Bacterial and Fungal Translocation and Intestinal Microbiota in Febrile Neutropenic Patients in Pediatric Onco-hematology

Status
Terminated
Phase
Study type
Observational
Enrollment
10 (actual)
Sponsor
Centre Hospitalier Universitaire de Nīmes · Academic / Other
Sex
All
Age
0 Years – 20 Years
Healthy volunteers
Not accepted

Summary

This pilot study aims to study intestinal bacterial and fungal translocation and the evolution of the intestinal microbiota in patients over the course of their medical surveillance to search for a link between dysbiosis and bacterial/fungal translocation, but also to better understand the elements involved in febrile episodes in these patients (lack of detection of blood microorganisms, translocation of constituent elements of these microorganisms, etc.). We hypothesize that the composition of the intestinal microbiota as well as the phenomenon of intestinal microbial translocation will have an influence on the occurrence of fever and/or bacteremia in neutropenic patients hospitalized in pediatric onco-hematology.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTEvaluation of microbial translocation and microbiotaBlood test from catheter already in place to determine microbial translocation and stool sample taken for microbiota analysis

Timeline

Start date
2018-04-13
Primary completion
2018-12-29
Completion
2018-12-29
First posted
2017-11-14
Last updated
2021-01-06

Locations

3 sites across 1 country: France

Source: ClinicalTrials.gov record NCT03342365. Inclusion in this directory is not an endorsement.