NCT03342274

Adapting the Diabetes Prevention Program for a Developing World Context

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 494 (actual)
• Sponsor: Children's Mercy Hospital Kansas City · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will examine whether an adapted version of \]he Diabetes Prevention Program (DPP) can be effective when delivered by community health workers (CHWs) in a poor urban community in South Africa. We will randomize existing groups that are part of an non-governmental organization's (NGO) chronic disease management program (anticipated cluster N = 54; anticipated individual N=540), to receive either the program or usual care (wait-list). The primary outcome analysis will compare percentage of baseline weight loss at Y1 between the program and usual care; however, after Y1 usual care participants will also receive the program and both groups will be followed for another year.

Conditions

• Weight Loss

Interventions

Type	Name	Description
BEHAVIORAL	Lifestyle Program	Participants will receive group weight loss sessions addressing healthy eating, exercise, and weight loss principles adapted from the Diabetes Prevention Program delivered by Community Health Workers.
OTHER	Usual Care	Usual care consists of chronic disease management through medication delivery and monitoring of weight, blood pressure, and blood glucose by Community Health Workers.

Timeline

• Start date: 2018-02-16
• Primary completion: 2019-11-13
• Completion: 2019-12-17
• First posted: 2017-11-14
• Last updated: 2022-05-13

Locations

1 site across 1 country: South Africa