Trials / Completed
CompletedNCT03337945
In Vivo Determination of Cytochrome P450 Activities in Patients With Liver Cirrhosis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 48 (actual)
- Sponsor
- University Hospital, Basel, Switzerland · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
Subjects will receive the "Basel phenotyping cocktail" capsule orally with 120-200ml tap water in fasted state. After intake peripheral venous blood samples will be drawn. 12 patients (male and female) with liver cirrhosis for each Child Pugh Category A, B, and C, and 12 age- and gender-matched healthy control subjects will be included (in total 48 participants).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | "Basel phenotyping cocktail" capsule | Oral intake of "Basel phenotyping cocktail" capsule and pharmacokinetics (PK) sampling |
Timeline
- Start date
- 2018-04-04
- Primary completion
- 2021-06-30
- Completion
- 2021-12-31
- First posted
- 2017-11-09
- Last updated
- 2022-05-23
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT03337945. Inclusion in this directory is not an endorsement.