NCT03336697

Determining the Microbiota Composition of the Middle Meatus in Parkinson's

Determining the Microbiota Composition of the Middle Meatus in Parkinson's Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 48 (actual)
• Sponsor: Rush University Medical Center · Academic / Other
• Sex: All
• Age: 45 Years – 75 Years
• Healthy volunteers: —

Summary

The exact cause of PD remains unknown, but current theories suggest that it results from a combination of hereditary or genetic factors (i.e. family traits ) and exposure to unknown substances in the environment. The purpose of this study is to investigate whether toxins produced by bacteria that live within the nasal canal (nose) and the intestines of people with PD might have a role in causing the disease. The investigators in this study would like to look at the types of bacteria that live in the nasal canals and intestines of PD subjects and compare them with those of subjects who do not have PD.

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Nasal swab	a nasal swab will be performed by a trained physician by gently passing of a cotton swab in the nasal passage to get samples from middle meatus. This will be performed under guide of nasal anterior endoscopy to visualize the location of sampling. The cotton swab heads will be placed in sterile tubes and frozen at -80°C until DNA extraction.

Timeline

• Start date: 2017-07-01
• Primary completion: 2019-03-10
• Completion: 2019-09-10
• First posted: 2017-11-08
• Last updated: 2019-10-04

Locations

1 site across 1 country: United States