Trials / Completed
CompletedNCT03335514
GALNT4 in Patients With Acute Coronary Syndrome
Changes of GALNT4 and the Relationship With PSGL-1on Monocytes and Hs-CRP in Blood of Patients With Coronary Heart Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (actual)
- Sponsor
- The First Affiliated Hospital of Dalian Medical University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The expression of GALNT4 in blood with acute coronary syndrome
Detailed description
Emerging evidences have linked GALNTs to cardiovascular disease or susceptibility to CAD.GALNT4, a member of the GalNAc-Ts family,contributes to the initiation of O-linked. Polymorphisms in GALNT4 have been linked with incidence of MI in an Irish population, probably that O-glycosylation of PSGL-1 by GalNAc-T4 may be important for many P-selectin mediated inflammation.However, there is few relevant studies about the expression of GALNT4 in patients with acute coronary syndrome.This study valuates the expression of GALNT4 in patients with acute coronary syndrome.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | expression of GALNT4 | Blood is obtained into ethylenediaminetetraacetic acid（EDTA） tubes from all subjects via antecubital venepuncture and the total RNA was extracted from blood.Realtime PCR was performed to measure the expression of GALNT4. |
Timeline
- Start date
- 2017-09-01
- Primary completion
- 2017-12-31
- Completion
- 2018-12-31
- First posted
- 2017-11-07
- Last updated
- 2019-03-19
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03335514. Inclusion in this directory is not an endorsement.