NCT03333525

Does Protein and Fat Content of Meal Increase Glucose Concentrations

Does High-Protein High-Fat Meal Increase Postprandial Glucose Concentrations and Meal-Time Insulin Requirements in Patients With Type 1 Diabetes on Basal-Bolus Insulin Regimen: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: TC Erciyes University · Academic / Other
• Sex: All
• Age: 16 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The study investigated the effects of fat protein counting (CFP) in addition to carbohydrate (CARB) counting for calculating prandial insulin dosage on blood glucose profile in patients with type 1 diabetes (T1D) on basal-bolus insulin therapy.

Detailed description

In this single center, crossover, randomized, controlled study, control meal (SM: standard meal using carbohydrate counting method) and three test meals (HPM: high protein meal using carbohydrate counting method, HPFM-a: high protein-fat meal using carbohydrate counting method and HPFM-b: high protein-fat meal using carbohydrate and fat-protein counting method) were compared on postprandial early (0-120 minutes), late (120-240 minutes) and total (0-240 minutes) glucose response.

Conditions

• Type 1 Diabetes Mellitus

Interventions

Type	Name	Description
OTHER	Calculation of insulin dosages for different meals	Calculation of insulin dosages For CARB counting meals using insulin-carbohydrate ratio for dosing mealtime boluses. For fat protein counting meal ICR and additionally fat-protein unit were used for dosing of mealtime boluses.

Timeline

• Start date: 2013-09-10
• Primary completion: 2014-02-20
• Completion: 2014-02-20
• First posted: 2017-11-07
• Last updated: 2017-11-07