NCT03330951

Glycemic Control and Iron Status in Diabetic Pregnancies - a Study of New Markers

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 41 (actual)
• Sponsor: Helse Stavanger HF · Other Government
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

This is an observational study at the Obstetrical outpatient clinic at Stavanger University Hospital. The main goal is to compare the current marker of glycemic control (glycated hemoglobin A1c, HbA1c) with glycated albumin in pregnancies with pregestational diabetes mellitus. Women with diabetes are at increased risk for adverse pregnancy outcomes. With improved glycemic control, the risk decreases. Glycated albumin is suggested to be a better marker for monitoring glycemic control in pregnancies because it reflects blood glucose for a shorter period than HbA1c (3 versus 8-12 weeks). Other studies have shown that HbA1c increases in pregnancy because of iron deficiency. The investigators want to investigate HbA1c, glycated albumin and iron status in diabetic pregnancies. The investigators will compare HbA1c and glycated albumin throughout pregnancy with the patient's own blood glucose measurements or data from CGM (continuous blood glucose monitoring). Blood samples for HbA1c and glycated albumin will be taken 6 times during pregnancy (week 12, 20, 24, 28, 32, 36).

Conditions

• Diabetes Mellitus Pregnancy

Timeline

• Start date: 2016-05-01
• Primary completion: 2019-02-01
• Completion: 2019-02-01
• First posted: 2017-11-06
• Last updated: 2020-01-27

Locations

1 site across 1 country: Norway