Trials / Completed
CompletedNCT03330782
Remifentanil for Preventing Propofol Injection Pain in Elderly Patients
Effect-site Concentration of Remifentanil for Preventing Propofol Injection Pain in Elderly Patients: A Comparison With Adult Patients
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 52 (actual)
- Sponsor
- Ajou University School of Medicine · Academic / Other
- Sex
- Male
- Age
- 19 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anesthetic drugs than younger patients. The purpose of this study was to investigate the optimal effect-site concentration of remifentanil for preventing injection pain during propofol induction in elderly patients by the Dixon's up-and-down method.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Remifentanil | Remifentanil was infused at predetermined effect-site concentration prior to propofol infusion (initial concentration: 3.0 ng/ml) in elderly patients (65-80 years) |
| DRUG | Remifentanil | Remifentanil was infused at predetermined effect-site concentration prior to propofol infusion (initial concentration: 3.0 ng/ml) in adult patients (20-60 years) |
Timeline
- Start date
- 2017-11-16
- Primary completion
- 2018-06-15
- Completion
- 2018-06-15
- First posted
- 2017-11-06
- Last updated
- 2019-07-05
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT03330782. Inclusion in this directory is not an endorsement.