Trials / Unknown
UnknownNCT03328871
The Combination Therapy of Fractional Laser and PRP Compared With Nanofat Grafting and PRP Synergy in Treating Striae Gravidarum.
The Combination Therapy of Fractional Laser and Platelet-Rich Plasma Injection Compared With Nanofat Grafting and Platelet-Rich Plasma Synergy in Treating Striae Gravidarum.
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- Sponsor
- First Affiliated Hospital of Jinan University · Academic / Other
- Sex
- Female
- Age
- 35 Years
- Healthy volunteers
- Not accepted
Summary
Nowadays, multiple treatment modalities have been applied clinically to treat striae gravidarum, such as laser therapy, microdermabrasion, platelet-rich plasma injection(PRP), etc. To some extent, these treatments can improve striae gravidarum. In this clinical trial, the investigators are going to treat striae gravidarum by using two different kinds of combination therapies. One is fractional laser and PRP injection synergy, and the other one is treated by nanofat grafting with PRP injection.
Detailed description
The investigators will pick out two areas of most severe striae gravidarum on a participant's abdomen. One of the areas will be treated by fractional laser once every three months for 2 times combined with PRP injection once a month for 6 times. Another area will be treated by nanofat grafting once every three months for 2 times and PRP therapy once a month for 6 times. The participants were asked to come back 1、3、6、9 months after treatment for further follow-up. Before and after the treatment, the striae gravidarum will be assessed subjectively by satisfaction assessment, dermatoscope and ultrasound, and objectively by immunohistochemical analysis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Fractional CO2 Laser | Fractional Carbon Dioxide Laser will be treated once every three months for 2 times. |
| PROCEDURE | Nanofat grafting | Nanofat grafting will be applied once every three months for 2 times. |
| PROCEDURE | Platelet-rich plasma (PRP) Injection | PRP Injection will be applied once a month for 6 times. |
Timeline
- Start date
- 2017-04-01
- Primary completion
- 2017-12-14
- Completion
- 2018-11-01
- First posted
- 2017-11-01
- Last updated
- 2018-05-25
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03328871. Inclusion in this directory is not an endorsement.