NCT03323892

Effect of Abstinence Duration on Embryo Development

Effect of Abstinence Duration on Embryo Development: a Prospective Sibling Oocyte Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Universitair Ziekenhuis Brussel · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim the investigators study is to analyze the embryo development if oocytes of the participants are injected with sperm from a longer or shorter (2 hours) abstinence duration.

Detailed description

Participants undergoing an IVF treatment, are asked to respect an abstinence duration of 2-7 days. This is to obtain a sufficient number of motile sperm. A recent investigation, analyzed the quality (number and motility) of a sperm sample produced after an abstinence duration of 4 to 7 days, followed by a second sperm sample 2 hours later. The second sample (after 2 hours) was able to produce sperm cells with a higher motility. Not only has this short abstinence duration of 2 hours a positive effect on the motility, it will also reduce the sperm DNA damage, which again has a positive effect on embryo development. Because participants need gametes of high quality to obtain embryos with a high quality, the investigators want to investigate what the effect is of abstinence duration on embryo development.

Conditions

• Embryo Development

Interventions

Type	Name	Description
OTHER	second masturbation	Husbands will be asked to produce a second sperm sample in the masturbatorium

Timeline

• Start date: 2017-11-01
• Primary completion: 2023-06-02
• Completion: 2023-12-31
• First posted: 2017-10-27
• Last updated: 2024-09-19

Locations

1 site across 1 country: Belgium