NCT03323112

Immune Responses in Health Care Personnel

Immune Responses to Influenza Vaccinations and Viruses Among Health Care Personnel

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Finnish Institute for Health and Welfare · Other Government
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

This is an investigator-initiated 10 year long open cohort observational study, aiming to increase the understanding of the humoral and cellular immunological mechanisms of vaccination against influenza, including effects of repeated vaccination, the duration of protection, immunity against circulating viruses, as well as factors affecting the immunological responses and immunity against other vaccine preventable infectious diseases among health care personnel.

Detailed description

Influenza vaccination is given according to the normal routine of Hospital District of Helsinki and Uusimaa (HUS) occupational health care. Blood samples will be collected before vaccination, 5 weeks after vaccination and 6 months after vaccination. Both the same participants and also new participants will be recruited each year. The analysis will be mainly descriptive.

Conditions

• Influenza

Interventions

Type	Name	Description
BIOLOGICAL	influenza vaccine	Vaccine for prevention of influenza. Vaccines change by influenza season.

Timeline

• Start date: 2017-10-18
• Primary completion: 2027-10-14
• Completion: 2027-10-14
• First posted: 2017-10-26
• Last updated: 2025-08-20

Locations

1 site across 1 country: Finland