Trials / Unknown
UnknownNCT03322969
Receiving Modified Chemotherapy Followed With Radical Resection After Neoadjuvant Chemotherapy
Receiving Modified Chemotherapy Followed With Radical Resection After Neoadjuvant Chemotherapy Versus Receiving the Original Chemotherapy in Locally Advanced Gastric Cancer: a Randomized Controlled Study
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Peking Union Medical College Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
For patients undergoing postoperative therapy for locally advanced gastric cancer after neoadjuvant chemotherapy, we assessed the utility of graded histologic regression of \<50% as the criterion of treatment change. Sixty patients will be enrolled to randomize into two groups：receiving modified chemotherapy and receiving the original chemotherapy.
Detailed description
For patients undergoing postoperative therapy for locally advanced gastric cancer after neoadjuvant chemotherapy, we assessed the utility of graded histologic regression of \<50% as the criterion of treatment change. Sixty patients will be enrolled to randomize into two groups：receiving modified chemotherapy and receiving the original chemotherapy. Overall survival and disease-free survival will be observed between two groups.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Paclitaxel/DDP | receiving the modified chemotherapy |
| DRUG | XELOX/SOX | receiving the original chemotherapy |
Timeline
- Start date
- 2017-08-23
- Primary completion
- 2022-08-01
- Completion
- 2023-08-01
- First posted
- 2017-10-26
- Last updated
- 2021-02-26
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03322969. Inclusion in this directory is not an endorsement.