NCT03322917

Ocular Surface Syndrome Post-lasik, Outcomes of Treatment With Platelet Rich Plasma

A Prospective Interventional Non-randomized and Non-comparative Series of Cases of Patiens Suffering Ocular Surface Syndrome Post-LASIK: Outcomes After the Treatment With Platelet Rich Plasma

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Vissum, Instituto Oftalmológico de Alicante · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the efficacy of autologous platelet-rich plasma eye drops (E-PRP) for the treatment of chronic ocular surface syndrome (OSS) following laser in situ keratomileusis (LASIK).

Detailed description

Prospective interventional consecutive case series including 156 eyes of 80 patients affected by chronic post-LASIK OSS who were treated with autologous E-PRP 6 times a day as monotherapy for 6 weeks. Assessment after treatment with E-PRP included: dry eye symptoms, change in corrected distance visual acuity (CDVA), corneal fluorescein staining (CFS) and conjunctival hyperemia.

Conditions

• Dry Eye After LASIK-Laser in Situ Keratomileusis

Interventions

Type	Name	Description
BIOLOGICAL	PRP autologous	Autologous platelet rich plasma: 1 drop / 6 times a day during 6 weeks

Timeline

• Start date: 2008-07-01
• Primary completion: 2013-01-17
• Completion: 2013-01-17
• First posted: 2017-10-26
• Last updated: 2017-12-04