NCT03321227

Effect of Eggs and Egg Components on Cognitive Performance and Appetite in School-aged Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: Toronto Metropolitan University · Academic / Other
• Sex: All
• Age: 9 Years – 14 Years
• Healthy volunteers: Accepted

Summary

The purpose of the present study is to determine the effects of eggs and egg components on cognitive performance and appetite in children aged 9-14 years, as well as to identify the underlying physiological mechanisms in this relationship.

Detailed description

Children will be asked to refrain from exercising the morning of their test day and inform researchers of any illness. Following a 12-hour overnight fast, children will consume a standardized breakfast of a cereal bar, fruit cup and orange juice at home (total 330 kcal). Children will be asked to avoid consumption of any other food, with the exception of water, until arrival at the laboratory 3 hours later. At the laboratory, five treatments of: (a) 2 whole eggs, (b) 2 egg whites, (c) 2 egg yolks, (d) full fat yogurt isocaloric to the 2 whole eggs, and (e) snack skipping will be provided to children 9-14 years on separate days at least 7 days apart. Cognitive performance, subjective emotion/mood, and subjective appetite will be measured for 90-minutes following snack consumption (n=25). Cognitive performance assessments will include learning and memory, spatial memory, attention and processing speed, and executive functions. In a subgroup of individuals (n=10), glucose, insulin, incretin hormones (glucagon like peptide1(GLP1) and gastric inhibitory polypeptide (GIP)),dipeptidyl peptidase 4 (DPP4), amino acids, fatty acids, and choline will be measured for 90-minutes following snack consumption.

Conditions

• Nutrition
• Cognitive Performance
• Appetite

Interventions

Type	Name	Description
OTHER	Snack skipping	No snack provided
OTHER	Whole eggs	2 whole large eggs scrambled, provided as a snack
OTHER	Egg whites	2 egg whites scrambled, provided as a snack
OTHER	Egg yolks	2 egg yolks scrambled, provided as a snack
OTHER	Yogurt	A serving of full fat yogurt that is isocaloric to the 2 whole eggs

Timeline

• Start date: 2018-04-09
• Primary completion: 2018-12-01
• Completion: 2019-12-01
• First posted: 2017-10-25
• Last updated: 2020-03-11

Locations

1 site across 1 country: Canada