NCT03320967

Copeptin and Arterial Hypotension in Critically Ill Paediatric and Neonatal Intensive Care Patients

COpeptin in Critically Ill Paediatric and Neonatal Intensive Care Patients and Its Association With Arterial Hypotension. A Single-centre Prospective Observational Study.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 170 (actual)
• Sponsor: Vincenzo Cannizzaro · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Not accepted

Summary

Blood copeptin will be measured during the routine treatment of neonates, children and adolescents on the Intensive Care Unit of the University Children's Hospital Zurich at different time points (admission, 12, 24, 48, 96, 168 hours after admission). These values will be primarily analysed for their variability and their association with arterial hypotension. Blood samples will be drawn together with otherwise medically indicated blood withdrawals to avoid extra harm. Further, copeptin values will be compared to clinical and vital parameters, all of them open-label available during clinical routine. Copeptin's predictive value for patients' outcome will be analysed as secondary outcome.

Conditions

• Arterial Hypotension in Critically Ill Neonatal and Pediatric Patients

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Copeptin in plasma	Copeptin will be measured in EDTA-Plasma. Samples will be stored for batch analyses later.

Timeline

• Start date: 2017-12-04
• Primary completion: 2019-06-30
• Completion: 2019-06-30
• First posted: 2017-10-25
• Last updated: 2019-07-05

Locations

1 site across 1 country: Switzerland