NCT03320135

EMD for Treatment of Proximal Class-II Furcation Involvements

Enamel Matriz Derivate for Treatment of Proximal Class II Furcation Defects: a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Universidade Estadual Paulista Júlio de Mesquita Filho · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is to evaluate the clinical response of proximal furcations treated with enamel matrix derivative proteins (EMD).

Detailed description

Proximal class-II furcation represents a challeng to periodontal therapy. Studies show that the ultrasonic non-surgical therapy doesn't work in these defects and the guided tissue regeneration therapy with membranes also demonstrates an unpredictable improvement. Therefore, enamel matrix derivative proteins (EMD) have been proposed as a periodontal regenerative procedure due to their fundamental role in cementum development.

Conditions

• Generalized Aggressive Periodontitis

Interventions

Type	Name	Description
PROCEDURE	Enamel matrix derivative proteins	Open flap debridement to enamel matrix derivative to treat proximal furcation involvements.
PROCEDURE	Open Flap debridement	Open flap debridement will be performed to decontaminate the proximal furcation involvements.

Timeline

• Start date: 2017-10-20
• Primary completion: 2018-10-20
• Completion: 2019-05-20
• First posted: 2017-10-25
• Last updated: 2019-06-05

Locations

1 site across 1 country: Brazil