NCT03320044

Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

Genetic Variations,Immuno-sequencing and Circulating Tumor DNA(ctDNA) for Early Diagnosis of Small Pulmonary Nodules

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Analyse immune repertoire and genetic mutations of benign and malignant pulmonary nodule，and evaluate peripheral blood detection for identifying nature of pulmonary nodule.

Detailed description

Early diagnosis of lung cancer is of vital importance in lung cancer treatment. This research will first analyse the features of immune repertoire and genetic mutations from tissue of benign and malignant pulmonary nodule，then explore the feasibility of detecting these features from peripheral blood sample, and finally evaluate peripheral blood detection of lung cancer related immune repertoire and genetic mutations for identifying nature of pulmonary nodule.

Conditions

• Carcinoma
• Non-small-cell Lung Cancer
• Lung Neoplasm

Timeline

• Start date: 2017-10-18
• Primary completion: 2018-07-31
• Completion: 2018-12-31
• First posted: 2017-10-24
• Last updated: 2019-01-09

Locations

1 site across 1 country: China