NCT03319264

Sarcopenia in Axial and Peripheral Spondyloarthropathies

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 106 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Spondylarthropathies (SpA) are among the most common chronic inflammatory rheumatisms in adults, responsible for a muscular loss or sarcopenia which can be very disabling, not much documented in the literature, and not yet studied in France. In addition, sarcopenia is associated with decreased physical activity and increased risk of falls and fractures. A better characterization of the determinants of this muscular loss will allow to better detect and take care of it. The aim is to conduct the first French study on the prevalence and severity of sarcopenia in patients with spondyloarthropathies and to study the variables that may be associated with it. Finally, we propose to evaluate obesity related to sarcopenia in these patients and compare them to cases matched for age and sex (from OFELY / STRAMBO cohorts, Lyon, FRANCE). This is a prospective interventional and monocentric study with minimal risks and constraints: patients will be included for one day for an evaluation of their sarcopenia by measuring their muscle strength, physical performance and body composition and recording of their socio-demographic and disease characteristics.

Conditions

• Spondylarthropathy
• Sarcopenia

Interventions

Type	Name	Description
OTHER	Dynamometry exam	Prehension strength of the main hand will be assessed thanks to dynamometry, in order to evaluate patient's muscular strength
OTHER	Walking test	A 4 metres walking test will be performed to assess patient's walking speed
RADIATION	DXA measurement	DXA measurement will be performed to assess patient's body composition
OTHER	SARQOL questionnaire	Patient's quality of life will be assessed thanks to the SARQOL questionnaire
BEHAVIORAL	Life habits Questionnaire	Life habits Questionnaire

Timeline

• Start date: 2017-11-02
• Primary completion: 2018-07-04
• Completion: 2018-07-04
• First posted: 2017-10-24
• Last updated: 2025-12-19

Locations

1 site across 1 country: France