NCT03318536

Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section

Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section - a Retrospective Analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 240 (actual)
• Sponsor: Johann Wolfgang Goethe University Hospital · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

The aim of the present study is to quantify the dose and usage of sympathomimetics used in caesarean section.

Detailed description

Recent metaanalysis showed significantly reduced hypotension and bradycardia in patients undergoing caesarean section in spinal anesthesia when 5-hydroxytryptamine 3 receptor antagonists were used prophylactically. Due to this fact in our clinic the standard procedure was changed. All patients for caesarean section receive Granisetron before spinal anesthesia. The aim of the present study is to evaluate the usage and dose of sympathomimetics during spinal anesthesia. Therefore the investigators will evaluate approximately 120 participants who received granisetron and 120 participants who did not receive 5-hydroxytryptamine 3 receptor antagonists.

Conditions

• Hypotension
• Cesarean Section Complications

Interventions

Type	Name	Description
DRUG	Granisetron Hydrochloride	Patients received Granisetron.
DRUG	No Granisetron	Patients who did not receive Granisetron.

Timeline

• Start date: 2017-10-05
• Primary completion: 2017-11-01
• Completion: 2018-02-01
• First posted: 2017-10-24
• Last updated: 2018-05-16

Locations

1 site across 1 country: Germany