NCT03318081

The Application of Cognitive Rehabilitation Therapy for Amphetamine-type Stimulants Addiction

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Shanghai Mental Health Center · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The computerized cognitive rehabilitation therapy will be used to treat amphetamine-type stimulant (ATS) addiction.

Detailed description

The deficits in executive functions related to prefrontal-striatal circuits play a vital role in ATS addiction and relapse, and proposed computerized cognitive rehabilitation therapy as the novel interventions. Focused on evaluating and training executive functions including working memory, inhibitory control, cognitive flexibility, and congitive bias concerning prefrontal-striatal circuits, neuropsychological tests, electroencephalography tests, magnetic resonance spectroscopy (MRS) and functional MRI will be used to evaluate the therapeutic effect of ATS addiction treatment as well as investigate the mechanisms. The study will be very helpful to develop novel interventions in clinical practice and decrease ATS-related harm for both the patients and their families.

Conditions

• Amphetamine Addiction

Interventions

Type	Name	Description
BEHAVIORAL	cognitive function rehabilitation and bias modification	cognitive rehabilitation focus on the deficits executive funcitin and elevated cognitive bias

Timeline

• Start date: 2017-10-20
• Primary completion: 2017-12-31
• Completion: 2018-05-01
• First posted: 2017-10-23
• Last updated: 2020-01-13

Locations

1 site across 1 country: China