NCT03315676

Efficacy of Proton Pump Inhibitors in Gastrointestinal Erosions and/or Ulcers

RCT Using Bonopurazan or Esomeprazole in Patients With NSAIDs-induced Erosions and/or Ulcers

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 124 (estimated)
• Sponsor: Shinshu University · Academic / Other
• Sex: All
• Age: 20 Years – 99 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to collect the data of clinical efficacy and safety after the usage of bonoprazon and esomeprazole when the patients take NSAIDs more than 2 weeks and have gastrointestinal symptoms who have had gastrointestinal erosions and/or ulcers in the past.

Conditions

• Gastrointestinal Erosions and/or Ulcers

Interventions

Type	Name	Description
DRUG	Oral Bonoprazan	To examine the efficacy of oral Bonoprazan in patients with NSAIDs-induced Erosions and/or Ulcers
DRUG	Oral Esomeprazol	To examine the efficacy of oral Esomeprazol in patients with NSAIDs-induced Erosions and/or Ulcers

Timeline

• Start date: 2017-11-01
• Primary completion: 2022-11-21
• Completion: 2025-09-04
• First posted: 2017-10-20
• Last updated: 2021-09-21

Locations

1 site across 1 country: Japan