NCT03314194

Plant Based Diet, Ethnicity, and the Gut Microbiome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (actual)
• Sponsor: Vanderbilt University Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Samples will be collected to determine human genetic variation, fecal and oral microbial communities, and metabolome products. Several evolutionary and ecological diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity is less than that between ethnicities; b) if microbiome variation is finely structured according to genetic relatedness; and c) if dietary variation impacts human genome x microbiome associations.

Detailed description

To characterize the human gut microbiome under highly controlled dietary intake in healthy normal weight adult participants who differ by ethnicity: White non-Hispanic and Black non-Hispanic adults. Samples will be collected to determine human genetic variation, fecal and oral microbial communities, and metabolome products. Several evolutionary and ecological diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity is less than that between ethnicities; b) if microbiome variation is finely structured according to genetic relatedness; and c) if dietary variation impacts human genome x microbiome associations.

Conditions

• Diet Modification
• Microbial Colonization

Interventions

Type	Name	Description
OTHER	Plant Based Diet	Plant Based Diet for 4 Days Compared to Habitual Diet

Timeline

• Start date: 2017-08-28
• Primary completion: 2019-06-30
• Completion: 2019-06-30
• First posted: 2017-10-19
• Last updated: 2021-07-16

Locations

1 site across 1 country: United States