Clinical Trials Directory

Trials / Unknown

UnknownNCT03313661

Co-administration of Cabergoline and Gliclazide Improve Glycemic Parameters and Lipid Profile in T2DM Patients

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
Sherief Abd-Elsalam · Academic / Other
Sex
All
Age
Healthy volunteers
Accepted

Summary

Evaluation of the glycemic efficacy of cabergoline on diabetic patients

Detailed description

Type 2 diabetes mellitus (DM) is a progressive metabolic disorder that is associated with basal hyperinsulinemia, insulin resistance and impaired insulin release. Glycemic control is a fundamental part of the management of type 2 DM and difficult to achieve. Different antidiabetic agents can handle diabetic metabolic abnormalities. The development of antidiabetic agentswith novel mechanisms of action is highly desirable. Cabergoline, a long acting D2 agonist, is expected to play a role in the glycemic control.

Conditions

Interventions

TypeNameDescription
DRUGCabergolinecabergoline 0.5 mg twice weekly within 2 hrs of awakening plus gliclazide
DRUGGliclazidegliclazide (60-120 mg)

Timeline

Start date
2017-10-14
Primary completion
2020-10-01
Completion
2020-12-01
First posted
2017-10-18
Last updated
2018-08-27

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT03313661. Inclusion in this directory is not an endorsement.