NCT03312959

Heavy Bupivacaine in Peribulbar Block

Heavy Bupivacaine Versus Plain Bupivacaine in Peribulbar Block

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Most of the ophthalmic procedures are performed under local anesthesia as the patient is often elderly and with diseases. This may increase the risk of morbidity and mortality under general anesthesia. Different eye blocks have been practiced with great success. Moreover, it is associated with less hemodynamic instability, less respiratory depression, better postoperative pain relief, and less nausea and vomiting than general anesthesia. It is also associated with a reduction in stress response, maintained oxygen saturation and cardiovascular stability, in addition to the production of good akinesia and anesthesia alleviating occulo-medullary reflexes, all make local anesthesia more superior and safe technique.

Detailed description

Peribulbar anesthesia is widely practiced now as a safe local block for cataract eye surgeries. However, the limited duration of these blocks was shown to be the main problem encountered intra-operatively. Therefore, additional top-up doses are usually needed to continue the operation. Many kinds of research tried to introduce solutions in order to prolong the duration of the local anesthetics used. Many researchers tried different volumes, doses and adjuvant to local anesthetics, and studied their effects There are many studies that evaluated the effect of baricity of local anesthetic on the potency of motor block and the duration of motor and sensory blockade. However, no properly designed randomized, controlled studies have evaluated the feasibility and reliability of baricity local anesthetic agents used for the peribulbar block. Aim of the work prospective, randomized study was conducted to evaluate the effects of the baricitized bupivacaine used for the peribulbar block in patients undergoing posterior segment surgeries.

Conditions

• Anesthetics, Local

Interventions

Type	Name	Description
DRUG	hyperbaric bupvacaine in Peribulbar block	hyperbaric bupivacaine in Peribulbar block will be injected in the posterior segment surgery
DRUG	isobaric bupvacaine in Peribulbar block	isobaric bupivacaine in Peribulbar block will be injected in the posterior segment surgery

Timeline

• Start date: 2017-11-01
• Primary completion: 2018-01-20
• Completion: 2018-01-31
• First posted: 2017-10-18
• Last updated: 2017-10-18

Locations

1 site across 1 country: Egypt