NCT03310450

Tour de Borobudur Troponin Study on Predictors and Synergistic Role of MDA and Hs-CRP Levels

Predictors of Cardiac Troponin Release After Tour de Borobudur 2017

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 94 (actual)
• Sponsor: Universitas Negeri Semarang · Academic / Other
• Sex: Male
• Age: 25 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Prospective observational study to determine predictors that related to cardiac troponin I (cTnI) release, malondialdehyde (MDA) and high sensitivity C Reactive Protein (hs-CRP) after Tour de Borobudur (TdB) 2017

Detailed description

Eligible Criteria: 1. minimum sample size of 80 men, non-athlete, participants of TdB 2. Classified into two groups: 160kms cycling and 100kms cycling participation 3. 25-55 years old 4. voluntary participate in the research 5. eligible in pre participatory physical examination and ECG test by the doctor 6. have no history of the previous acute coronary syndrome (ACS) Measurements: Interview for determining predictors of sports participation history, medical history, family medical history and Rate of Perceived Exertion Measurement and examination to determine: anthropometry parameters, clinical conditions (Systolic BP, Diastolic BP, hemoglobin levels, T-cholesterol and HDL-C levels, the intensity in cycling activities (mileage, velocity, duration, and time for resting), hemodynamic responses (average and maximum heart rate, Karvonen Index), and Hydration status Other outcome measurements; pre and post-TdB 2017 measurements of cTnI, MDA, and hs-CRP

Conditions

• Heart Arrest
• Sport Injury
• Inflammatory Response
• Oxidative Stress

Interventions

Type	Name	Description
OTHER	140kms cycling	Main exposure is long distance cycling touring (TdB/NC) consists of three groups; 140kms, 100kms, and 240kms (investigator did not give any treatment/intervention, just observed the cycling touring event)

Timeline

• Start date: 2017-10-28
• Primary completion: 2017-11-11
• Completion: 2018-05-05
• First posted: 2017-10-16
• Last updated: 2019-10-10
• Results posted: 2019-10-02

Locations

1 site across 1 country: Indonesia